Description

Actinomycin D2 CAS NO 72751-56-5 is a potent antibiotic and antitumor agent belonging to the actinomycin family of chromopeptides. This compound is of significant value in biochemical and pharmaceutical research due to its ability to intercalate into DNA and inhibit transcription. It is primarily needed by research institutions, pharmaceutical developers, and biotechnology companies engaged in oncology research, molecular biology studies, and the development of novel chemotherapeutic agents.

Application

• Oncology Research: Used as a reference standard and investigative tool in studying cancer cell apoptosis, DNA damage response, and mechanisms of chemotherapy resistance.
• Molecular Biology: Employed as a potent inhibitor of RNA polymerase to study transcriptional regulation and gene expression in vitro.
• Biochemical Studies: Serves as a model compound for researching DNA intercalation and the biological activity of chromopeptides.
• Pharmaceutical Development: Acts as a key intermediate or reference material in the synthesis and quality control of related antitumor compounds.
• Cell Culture & Virology: Utilized in selective media and experimental protocols to inhibit cellular transcription in specific research applications.
• Academic Research: A critical reagent for universities and institutes conducting fundamental research in biochemistry, pharmacology, and cancer biology.

Basic Information

Product Name	Actinomycin D2
CAS No.	72751-56-5
Molecular Formula	C62H86N12O16
Molecular Weight	1279.42 g/mol
Synonyms	Actinomycin D2; Actinomycin IV; Actinomycin D Variant; 7-Deoxyactinomycin D; Actinomycin D2 (7-Deoxy); Dactinomycin D2; NSC 328153; Cosmegen D2 (related)
EINECS	Contact for details

Quality Control

Our Actinomycin D2 is produced and tested under strict quality management systems to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines to support our clients' quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment and handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Orange-red to red crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.