Description

Hydrocortisone Butyrate Propionate is a synthetic corticosteroid ester, a potent topical anti-inflammatory agent. This high-purity active pharmaceutical ingredient (API) is critical for developing advanced dermatological treatments with enhanced efficacy and stability. It is primarily required by pharmaceutical manufacturers and R&D facilities specializing in topical corticosteroids for conditions like eczema, psoriasis, and dermatitis.

Application

• Topical Corticosteroid Formulations: Primary active ingredient in creams, ointments, and lotions for treating inflammatory skin conditions.
• Dermatological R&D: Used in research and development of new topical anti-inflammatory and anti-pruritic medications.
• Pharmaceutical Intermediates: Serves as a key intermediate in the synthesis of more complex steroid-based APIs.
• Veterinary Medicine: Incorporated into topical preparations for treating skin inflammation in animals.
• Cosmeceuticals: Potential use in specialized cosmetic products targeting skin redness and irritation, under strict regulatory oversight.

Basic Information

Item	Detail
Product Name	Hydrocortisone Butyrate Propionate
CAS No.	72590-77-3
Molecular Formula	C28H40O7
Molecular Weight	488.62 g/mol
Synonyms	Hydrocortisone 17-Butyrate 21-Propionate; Pivalone; 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione 17-butyrate 21-propionate; HBP; (11β)-11,17,21-Trihydroxypregn-4-ene-3,20-dione 17-butyrate 21-propionate
EINECS	Contact for details

Quality Control

Our Hydrocortisone Butyrate Propionate is manufactured under strict quality systems. Each batch is tested to meet high-purity standards suitable for pharmaceutical applications, with comprehensive analysis including identity, assay, and impurity profile. A Certificate of Analysis (COA) documenting compliance with agreed specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to almost white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.