Description

16Alpha-Ethyl-21-Hydroxy-19-Norpregna-4,9-Diene-3,20-Dione is a high-purity synthetic steroid intermediate with the CAS registry number 72137-42-9. This compound is a critical building block in the synthesis of advanced pharmaceutical active ingredients, offering a defined stereochemical structure essential for precise biological activity. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development and production of novel steroidal drugs, including potential anti-inflammatory and hormonal therapies.

Application

• Pharmaceutical Intermediate: A key starting material or intermediate in the multi-step synthesis of novel steroidal active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry research for structure-activity relationship (SAR) studies and the development of new therapeutic agents.
• Steroid Derivative Synthesis: Serves as a precursor for creating modified steroid analogs with targeted pharmacological properties.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical laboratories.
• Process Chemistry: Utilized in scale-up and process optimization for the commercial manufacturing of steroidal compounds.

Basic Information

Product Name	16Alpha-Ethyl-21-Hydroxy-19-Norpregna-4,9-Diene-3,20-Dione
CAS No.	72137-42-9
Molecular Formula	C₂₂H₃₀O₃
Molecular Weight	342.47 g/mol
Synonyms	16α-Ethyl-21-hydroxy-19-norpregna-4,9-diene-3,20-dione; 16α-Ethyl-21-hydroxy-19-nor-4,9-pregnadiene-3,20-dione; 16α-Ethyl-19-nor-4,9-pregnadiene-3,20-dione-21-ol; 16α-Ethyl-21-hydroxy-19-nor-4,9-pregnadiene-3,20-dione; 16α-Ethyl-21-hydroxy-19-nor-δ⁴,⁹-pregnadiene-3,20-dione; 16α-Ethyl-21-hydroxy-19-nor-δ⁴,⁹-pregnadiene-3,20-dione; 16α-Ethyl-21-hydroxy-19-nor-δ⁴,⁹-pregnadiene-3,20-dione; 16α-Ethyl-21-hydroxy-19-nor-δ⁴,⁹-pregnadiene-3,20-dione
EINECS	Contact for details

Quality Control

Our 16Alpha-Ethyl-21-Hydroxy-19-Norpregna-4,9-Diene-3,20-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specific results for your quality assurance records.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.