Description

(8S,10S)-10-[(3-Amino-2,3,6-Trideoxy-α-L-Lyxo-Hexopyranosyl)Oxy]-8-Ethyl-8,11-Dihydroxy-7,8,9,10-Tetrahydro-1-Methoxy-5,12-Naphthacenedione is a structurally complex anthracycline derivative, a class of compounds known for significant biological activity. This compound is of critical importance as a key intermediate or reference standard in advanced pharmaceutical research and development. It is primarily needed by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions focused on oncology and antibiotic drug discovery.

Application

• Pharmaceutical Reference Standard: Used for analytical method development, validation, and quality control in the production of complex active pharmaceutical ingredients (APIs).
• Oncology Research Intermediate: Serves as a crucial building block or precursor in the synthesis of novel anthracycline-based chemotherapeutic agents.
• Biochemical Research: Employed in studies investigating the mechanism of action of DNA-intercalating agents and topoisomerase inhibitors.
• Antibiotic Development: Acts as a structural template for the development of new generations of antibiotics targeting resistant bacterial strains.
• Process Chemistry: Utilized in scaling up and optimizing synthetic routes for complex natural product derivatives under GMP conditions.
• Academic Research: Provides a specialized chemical tool for universities and research institutes studying organic synthesis, medicinal chemistry, and pharmacology.

Basic Information

Product Name	(8S,10S)-10-[(3-Amino-2,3,6-Trideoxy-α-L-Lyxo-Hexopyranosyl)Oxy]-8-Ethyl-8,11-Dihydroxy-7,8,9,10-Tetrahydro-1-Methoxy-5,12-Naphthacenedione
CAS No.	71800-92-5
Molecular Formula	C26H31NO9
Molecular Weight	501.53 g/mol
Synonyms	8-Ethyl-8,11-dihydroxy-1-methoxy-10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-5,12-naphthacenedione; 10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-ethyl-8,11-dihydroxy-7,8,9,10-tetrahydro-1-methoxy-5,12-naphthacenedione; 4-Demethoxy-7-O-methylcarminomycin; 4-Demethoxy-7-O-methylcarminomycin I; Carminomycin I, 4-demethoxy-7-O-methyl-; Anthracycline derivative (8S,10S)-isomer
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to confirm identity and purity. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We support research and development with materials suitable for use as analytical reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. Due to its sensitivity to oxidation, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability. Keep the container in a dry, well-ventilated area.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 3.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.