Description

8-(1-Hydroxyethyl)-10-[(3-Amino-2,3,6-Trideoxy-α-L-Lyxo-Hexopyranosyl)Oxy]-7,8,9,10-Tetrahydro-8,11-Dihydroxy-1-Methoxy-5,12-Naphthacenedione is a complex anthracycline derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for the synthesis and analysis of specialized chemotherapeutic agents. It is primarily sought by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in oncology drug development and analytical method validation. The structural complexity of this molecule demands high-purity synthesis and stringent quality control for reliable research outcomes.

Application

• Pharmaceutical Intermediate: Key building block in the synthetic pathway for novel anthracycline-based anticancer drugs.
• Reference Standard: High-purity material used for qualitative and quantitative analysis (HPLC, LC-MS) in pharmaceutical quality control and regulatory submissions.
• Biochemical Research: Tool compound for studying the structure-activity relationships (SAR) of anthracyclines, their mechanism of action, and interactions with DNA.
• Academic Research: Used in university and institutional labs for medicinal chemistry projects focused on oncology and antibiotic development.
• Process Development: Serves as a benchmark in scaling up and optimizing the manufacturing processes for complex active pharmaceutical ingredients (APIs).

Basic Information

Product Name	8-(1-Hydroxyethyl)-10-[(3-Amino-2,3,6-Trideoxy-α-L-Lyxo-Hexopyranosyl)Oxy]-7,8,9,10-Tetrahydro-8,11-Dihydroxy-1-Methoxy-5,12-Naphthacenedione
CAS No.	71800-90-3
Molecular Formula	C₂₇H₃₃NO₁₁
Molecular Weight	547.55 g/mol
Synonyms	10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-(1-hydroxyethyl)-7,8,9,10-tetrahydro-8,11-dihydroxy-1-methoxy-5,12-naphthacenedione; 4-Demethoxy-11-deoxy-13-dihydrodaunorubicin; 4-DM-11-deoxy-13-dihydrodaunorubicin; Carminomycin I derivative; Anthracycline derivative 71800-90-3
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to strict quality management systems. Every batch is subjected to comprehensive analytical characterization using techniques including HPLC, NMR, and mass spectrometry to confirm identity and purity. A Certificate of Analysis (COA) detailing all test results is provided with each shipment. We support development and regulatory needs with materials suitable for use as research-grade and reference standard applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	Red to orange-red powder
Identification (HPLC)	Conforms to reference
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.