Description

4-(Dimethylamino)-3-(Trifluoromethyl)Benzonitrile is a high-value, multi-functional aromatic nitrile building block featuring both dimethylamino and trifluoromethyl substituents. This compound is essential for advanced organic synthesis, offering a unique combination of electron-donating and electron-withdrawing groups that enable precise tuning of molecular properties. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for constructing sophisticated ligands in catalysis and as a building block for functional materials.
• Organic Electronic Materials: Investigated for use in the synthesis of charge-transport materials and dyes for optoelectronic applications.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D focused on heterocyclic chemistry, fluorochemistry, and the creation of novel chemical entities.

Basic Information

Product Name	4-(Dimethylamino)-3-(Trifluoromethyl)Benzonitrile
CAS No.	71145-96-5
Molecular Formula	C10H9F3N2
Molecular Weight	214.19 g/mol
Synonyms	3-(Trifluoromethyl)-4-(dimethylamino)benzonitrile; 4-(Dimethylamino)-α,α,α-trifluoro-m-tolunitrile; 4-Cyano-2-(dimethylamino)benzotrifluoride; 2-(Dimethylamino)-α,α,α-trifluoro-p-tolunitrile; 4-(N,N-Dimethylamino)-3-(trifluoromethyl)benzonitrile; 3-Trifluoromethyl-4-dimethylaminobenzonitrile; 4-Dimethylamino-3-trifluoromethylbenzonitrile
EINECS	Contact for details

Quality Control

Our 4-(Dimethylamino)-3-(Trifluoromethyl)Benzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and a Certificate of Analysis (COA) with every shipment, detailing all critical quality parameters. Our quality commitment supports applications requiring high-purity intermediates for GMP and non-GMP research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.