Description

4-Amino-5,5,5-Trifluoropentanoic Acid is a high-value, non-natural amino acid derivative characterized by its trifluoromethyl group, which imparts unique physicochemical properties critical for advanced chemical synthesis. This compound serves as a versatile and sophisticated building block for the development of novel pharmaceuticals and agrochemicals, where the introduction of fluorine atoms is a key strategy to modulate bioavailability, metabolic stability, and binding affinity. It is primarily utilized by research institutions and industrial R&D departments focused on medicinal chemistry, peptide mimetics, and the creation of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for incorporating fluorine into bioactive molecules to enhance their pharmacokinetic and pharmacodynamic profiles.
• Agrochemical Synthesis: Used in the design and production of advanced herbicides, fungicides, and pesticides, where the trifluoromethyl group can improve efficacy and environmental stability.
• Peptide Modification: Employed as a non-proteinogenic amino acid analog for creating modified peptides with increased resistance to enzymatic degradation and altered biological activity.
• Fluorine Chemistry Research: Serves as a fundamental reagent in academic and industrial laboratories studying the effects of fluorine substitution in organic molecules.
• Ligand and Catalyst Development: Utilized in the synthesis of specialized ligands and organocatalysts for asymmetric synthesis and other advanced chemical transformations.
• Material Science Precursor: Acts as a starting material for synthesizing fluorinated polymers or specialty chemicals with specific surface properties.

Basic Information

Product Name	4-Amino-5,5,5-Trifluoropentanoic Acid
CAS No.	70961-08-9
Molecular Formula	C5H8F3NO2
Molecular Weight	171.12 g/mol
Synonyms	5,5,5-Trifluoro-4-aminopentanoic Acid; 4-Amino-5,5,5-trifluorovaleric Acid; 5,5,5-Trifluoroleucine precursor; 4-Azaniumyl-5,5,5-trifluoropentanoate; 5,5,5-Trifluoro-DL-norleucine analog; γ-Amino-γ-trifluoromethylbutyric Acid; 4-Amino-5,5,5-trifluoropentanoate
EINECS	Contact for details

Quality Control

Our 4-Amino-5,5,5-Trifluoropentanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and specific tests for residual solvents and heavy metals to ensure it meets the stringent requirements for research and production use. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.