Description

n-Benzyladriamycin CAS NO 70878-56-7 is a chemically modified derivative of the anthracycline antibiotic doxorubicin, designed to enhance therapeutic properties and reduce systemic toxicity. This compound is of significant interest for advanced pharmaceutical research and development, particularly in the field of oncology. It is primarily utilized by research institutions, pharmaceutical manufacturers, and biotechnology companies engaged in the synthesis of novel chemotherapeutic agents and targeted drug delivery systems.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of next-generation anthracycline-based anticancer drugs.
• Biomedical Research: Used in in vitro and in vivo studies to investigate structure-activity relationships, mechanism of action, and efficacy against various cancer cell lines.
• Drug Discovery Programs: A critical building block for medicinal chemists exploring modifications to the doxorubicin scaffold to improve selectivity and reduce cardiotoxicity.
• Conjugate Synthesis: Employed in the creation of antibody-drug conjugates (ADCs) or polymer-drug conjugates for targeted cancer therapy.
• Academic Research: Utilized in university and institutional labs for fundamental studies on DNA intercalation and topoisomerase II inhibition.

Basic Information

Product Name	n-Benzyladriamycin
CAS No.	70878-56-7
Molecular Formula	C₃₄H₃₅NO₁₂
Molecular Weight	649.64 g/mol
Synonyms	N-Benzyladriamycin; N-Benzyl-14-hydroxydaunomycin; 7-O-(2,6-Dideoxy-α-L-lyxo-hexopyranosyl)-N-benzyladriamycinone; Adriamycin, N-benzyl-; N-Benzyladriamycinone 7-(2,6-dideoxy-α-L-lyxo-hexopyranoside); N-Benzyl-14-hydroxydaunorubicin; (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-glycoloyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione, N-benzyl-
EINECS	Contact for details

Quality Control

Our n-Benzyladriamycin is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency suitable for research and development. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This product is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and potency.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.