Description

Trifluoromethylcarbonocyanidimidic Acid Trimethylsilyl Ester is a specialized organosilicon reagent featuring a reactive cyanoimidate group protected by a trimethylsilyl moiety. This compound is a critical building block in advanced organic synthesis, particularly for introducing the trifluoromethyl group and constructing complex heterocyclic frameworks. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of novel drug candidates, especially those requiring trifluoromethylated bioactive molecules.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides where the CF3 group enhances biological activity and metabolic stability.
• Material Science Research: Employed in the development of specialty polymers and advanced materials with unique surface properties.
• Fluorination Chemistry: Acts as a versatile reagent for introducing fluorine-containing functional groups into complex organic molecules under mild conditions.
• Heterocycle Construction: Facilitates the synthesis of nitrogen-containing heterocycles, which are prevalent scaffolds in medicinal chemistry.

Basic Information

Product Name	Trifluoromethylcarbonocyanidimidic Acid Trimethylsilyl Ester
CAS No.	70856-22-3
Molecular Formula	C7H10F3N2OSi
Molecular Weight	224.25 g/mol
Synonyms	Trimethylsilyl Trifluoromethylcarbonocyanidimidate; (Trimethylsilyloxy)(trifluoromethyl)carbonimidic Cyanide; Trifluoromethyl(trimethylsilyloxy)carbonimidic Cyanide; TMS-Trifluoromethylcarbonocyanidimidate; CF3C(=NCN)OSi(CH3)3
EINECS	Contact for details

Quality Control

Our Trifluoromethylcarbonocyanidimidic Acid Trimethylsilyl Ester is produced under stringent quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We employ advanced analytical techniques including NMR, HPLC, and GC-MS for comprehensive characterization. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and highly volatile nature, this material should be stored under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended storage temperature is 2-8°C. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture ingress and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.