Description

Leurubicin CAS NO 70774-25-3 is a synthetic anthracycline derivative with significant pharmacological interest. This compound is valued for its potential as a key intermediate or reference standard in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and synthesis of novel chemotherapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel anthracycline-based anticancer agents.
• Biochemical Research: Used as a reference standard in studies investigating the structure-activity relationships (SAR) of DNA-intercalating drugs.
• Oncology R&D: Employed in preclinical research for evaluating new mechanisms of action and efficacy against various cancer cell lines.
• Analytical Standard: Provides a high-purity benchmark for quality control and method development in analytical laboratories (HPLC, LC-MS).
• Academic Research: Utilized in university and institutional labs for chemical biology and medicinal chemistry projects.

Basic Information

Product Name	Leurubicin
CAS No.	70774-25-3
Molecular Formula	C26H29NO9
Molecular Weight	499.51 g/mol
Synonyms	4'-O-Methyldoxorubicin; 4'-O-Methyladriamycin; 4'-O-Methyl-14-hydroxydaunomycin; 4'-O-Methyldoxorubicin hydrochloride; Leurubicin hydrochloride; NSC 382070; (8S,10S)-10-[(3-Amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-8-glycoloyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione; 4'-O-Methyladriamycinone glycoside
EINECS	Contact for details

Quality Control

Our Leurubicin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.