Description

Peplomycin Sulfate is a bleomycin-derived antitumor antibiotic, valued for its potent chemotherapeutic activity. This compound is critical for pharmaceutical research and development, particularly in the study of novel cancer treatments. It is primarily needed by research institutions, pharmaceutical manufacturers, and biotechnology companies engaged in oncology drug discovery and formulation.

Application

• Pharmaceutical Active Ingredient (API): Serves as a key component in the research and development of injectable chemotherapeutic agents.
• Oncology Research: Used as a reference standard and experimental compound in biochemical and pharmacological studies targeting various cancer cell lines.
• Mechanism of Action Studies: Employed to investigate DNA cleavage and inhibition of tumor cell proliferation.
• Preclinical Development: Utilized in animal model studies to evaluate the efficacy and toxicity profiles of bleomycin analogues.
• Analytical Standard: Acts as a high-purity standard for quality control (QC) and quality assurance (QA) in pharmaceutical analysis using HPLC or other chromatographic methods.

Basic Information

Product Name	Peplomycin Sulfate
CAS No.	70384-29-1
Molecular Formula	C61H88N18O21S2 • xH2SO4
Molecular Weight	Approx. 1500 (base) - Contact for exact sulfate salt form.
Synonyms	PEP Sulfate; Peplomycin Sulphate; (3-{[(2-{[(2-{[(2-{[(2-{[(2-{[(5-Amino-5-carboxypentanoyl)amino]acetyl}amino)acetyl]amino}acetyl)amino]acetyl}amino)acetyl]amino}ethyl)amino]carbonyl}propyl)dimethylsulfonium]bleomycin sulfate; NK-631; PEP-Bleo; NK 631
EINECS	Contact for details

Quality Control

Our Peplomycin Sulfate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and potency, meeting high standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), related substances, water content, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C) or as indicated on the label. This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 95.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water (Karl Fischer)	≤ 8.0%
Residue on Ignition	≤ 1.0%
Biological Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.