Description

7-n-(4-Hydroxyphenyl)Mitomycin C is a chemically modified derivative of the potent antitumor antibiotic Mitomycin C, designed to alter its pharmacological profile and biological activity. This compound is of significant interest in pharmaceutical research for the development of novel chemotherapeutic agents and targeted drug conjugates. It is primarily utilized by research institutions and pharmaceutical companies engaged in oncology drug discovery, mechanism of action studies, and the synthesis of advanced pharmaceutical intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel anticancer drug candidates and targeted therapies.
• Biochemical Research: Used in laboratory studies to investigate structure-activity relationships (SAR) of mitomycin analogs and their interaction with DNA.
• Antitumor Agent Development: Acts as a precursor for the development of prodrugs and antibody-drug conjugates (ADCs) aimed at reducing systemic toxicity.
• Academic Research: Employed in universities and research institutes for studying the mechanisms of bioreductive alkylation and DNA cross-linking.
• Reference Standard: Can be used as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	7-n-(4-Hydroxyphenyl)Mitomycin C
CAS No.	70343-57-6
Molecular Formula	C20H21N3O7
Molecular Weight	415.40 g/mol
Synonyms	7-(4-Hydroxyphenyl)mitomycin C; Mitomycin C, 7-[(4-hydroxyphenyl)amino]-; 7-N-(p-Hydroxyphenyl)mitomycin C; 7-N-(4-Hydroxyphenyl)mitomycin; 7-(4-Hydroxyphenylamino)mitomycin C; 7-N-(4-Hydroxyphenyl)-mitomycin C
EINECS	Contact for details

Quality Control

Our 7-n-(4-Hydroxyphenyl)Mitomycin C is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for research and development purposes. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for pharmaceutical intermediates, and specifications can be provided to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. This material is light-sensitive (store away from light). Keep the container in a dry, cool, and well-ventilated area. For long-term storage, consider storing under inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	Solid (Color to be specified per lot)
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.