Description

Mindodilol is a high-purity pharmaceutical intermediate and research chemical with the CAS registry number 70260-53-6. This compound is of significant interest in the development and synthesis of advanced active pharmaceutical ingredients (APIs), particularly within the cardiovascular therapeutic area. It is essential for pharmaceutical manufacturers, R&D laboratories, and academic institutions engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of β-adrenergic blocking agents (β-blockers) and related cardiovascular drugs.
• Active Pharmaceutical Ingredient (API) Research: Serves as a crucial precursor or reference standard in the research and development of new therapeutic compounds.
• Chemical Synthesis: Used in organic synthesis for the construction of complex molecules containing specific chiral centers and functional groups.
• Biochemical Research: Employed in pharmacological studies to investigate receptor binding and enzyme inhibition mechanisms.
• Process Development & Scale-up: Critical for optimizing manufacturing routes and ensuring consistent quality in commercial API production.
• Analytical Reference Standard: Provides a high-purity benchmark for quality control (QC) and analytical method development (e.g., HPLC, GC).

Basic Information

Product Name	Mindodilol
CAS No.	70260-53-6
Molecular Formula	C16H24N2O3
Molecular Weight	292.38 g/mol
Synonyms	1-(tert-Butylamino)-3-[(5,6,7,8-tetrahydro-cis-6,7-dihydroxy-1-naphthyl)oxy]-2-propanol; (6R,7S)-6,7-Dihydroxy-1-[(1RS)-1-hydroxy-2-[(1,1-dimethylethyl)amino]ethoxy]-1,2,3,4-tetrahydronaphthalene; Mindodilol Hydrochloride (salt form); L 657,743; L-657743
EINECS	Contact for details

Quality Control

Our Mindodilol is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability. We provide comprehensive analytical data to support its use in regulated environments. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each batch, confirming compliance with client specifications and relevant industry guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single unknown impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.