Description

Dexamethasone Sulfate Ester is a key pharmaceutical intermediate and a chemically modified derivative of the potent glucocorticoid dexamethasone. This compound is critical for enhancing the solubility and bioavailability of the parent drug, enabling more effective formulation development. It is primarily utilized by pharmaceutical manufacturers and research institutions in the synthesis of advanced corticosteroid medications and for investigative studies in endocrinology and inflammation.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of water-soluble dexamethasone prodrugs and conjugates.
• Drug Formulation Research: Used to improve the solubility profile and delivery mechanisms of corticosteroid-based therapeutics.
• Biochemical Research: Serves as a tool compound in studies investigating glucocorticoid receptor activity and steroid metabolism pathways.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Veterinary Medicine: Potential use in the development of anti-inflammatory and immunosuppressive treatments for animals.

Basic Information

Product Name	Dexamethasone Sulfate Ester
CAS No.	7793-27-3
Molecular Formula	C22H29FO8S
Molecular Weight	472.52 g/mol
Synonyms	Dexamethasone 21-Sulfate; Dexamethasone Sulfate; 9-Fluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-(hydrogen sulfate); Dexamethasone Hydrogen Sulfate; Dexamethasone 21-(Hydrogen Sulfate) Ester
EINECS	Contact for details

Quality Control

Our Dexamethasone Sulfate Ester is manufactured and tested under a strict quality management system. We provide material that meets high-purity standards suitable for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is supplied with each batch to ensure traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.