Description

Anthramycin 11-Methyl Ether is a chemically modified derivative of the pyrrolo[1,4]benzodiazepine antibiotic anthramycin. This compound is valued for its role as a key intermediate in pharmaceutical research and development, particularly in the study of DNA-binding antitumor agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in oncology drug discovery and the synthesis of novel bioactive molecules. The product is supplied with a focus on high purity and batch-to-batch consistency to support critical research applications.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel antitumor compounds and DNA-targeting agents.
• Oncology Research: Used in biochemical and pharmacological studies to investigate mechanisms of action related to DNA alkylation and inhibition of nucleic acid synthesis.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to develop derivatives with optimized potency and reduced toxicity.
• Biochemical Tool Compound: Acts as a reference standard in assays designed to screen for DNA-interactive properties of new chemical entities.
• Academic Research: Utilized in university and institutional labs for fundamental studies in chemical biology and anticancer drug mechanisms.

Basic Information

Product Name	Anthramycin 11-Methyl Ether
CAS No.	7683-27-4
Molecular Formula	C17H16N2O4
Molecular Weight	312.32 g/mol
Synonyms	11-Methoxyanthramycin; NSC 267213; 5,10,11,11a-Tetrahydro-9,11-dihydroxy-8-methyl-5-oxo-1H-pyrrolo[2,1-c][1,4]benzodiazepin-2-acrylamide, 11-methyl ether; Anthramycin methyl ether; 11-O-Methylanthramycin
EINECS	Contact for details

Quality Control

Our Anthramycin 11-Methyl Ether is produced and handled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, MS) for structural confirmation, to ensure it meets the high standards required for research applications. A Certificate of Analysis (COA) detailing specific results for identity, purity, and impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.