Description

Prednisolone Tebutate is a synthetic glucocorticoid ester derivative of prednisolone, widely recognized for its potent anti-inflammatory and immunosuppressive properties. This compound is a critical intermediate and active pharmaceutical ingredient (API) in the development of specialized corticosteroid formulations. It is primarily utilized by pharmaceutical manufacturers and research institutions focused on advanced therapeutic solutions for inflammatory and autoimmune conditions.

Application

• Pharmaceutical API: A key intermediate in the synthesis of injectable and topical corticosteroid medications.
• Anti-inflammatory Formulations: Used in the development of treatments for conditions like arthritis, dermatitis, and allergic reactions.
• Ophthalmic Preparations: Serves as an active ingredient in eye drops and ointments for treating ocular inflammation.
• Veterinary Medicine: Employed in anti-inflammatory and immunosuppressive therapies for animals.
• Research & Development: A standard compound in pharmacological studies exploring glucocorticoid receptor activity and steroid metabolism.
• Dermatological Products: Used in creams and lotions for managing severe skin conditions such as psoriasis and eczema.

Basic Information

Product Name	Prednisolone Tebutate
CAS No.	7681-14-3
Molecular Formula	C₂₆H₃₆O₆
Molecular Weight	444.56 g/mol
Synonyms	Prednisolone 21-Tert-Butylacetate; Prednisolone Tert-Butylacetate; 11β,17α,21-Trihydroxypregna-1,4-diene-3,20-dione 21-(2,2-Dimethylacetate); Tebutate; NSC-39415; SQ-15102; U-6750A; Prednisolone 21-(3,3-Dimethylbutyrate)
EINECS	231-665-0

Quality Control

Our Prednisolone Tebutate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by IR and NMR spectroscopy, to ensure compliance with pharmaceutical-grade standards. Certificates of Analysis (COA) detailing all specifications are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.