Description

2-Fluoro-3,4-Dimethoxyphenylacetonitrile is a versatile fluorinated aromatic nitrile building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both electron-donating methoxy groups and a reactive nitrile function adjacent to a fluorine atom, makes it a critical intermediate for constructing complex pharmacophores. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and material science.
• Advanced Material Research: Employed in the synthesis of fluorinated liquid crystals, organic semiconductors, and polymers with tailored electronic properties.
• Chemical Biology Probes: Useful for creating fluorescent tags or molecular probes to study biological processes.
• Custom Synthesis and Contract Manufacturing: A high-value starting material for fine chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name	2-Fluoro-3,4-Dimethoxyphenylacetonitrile
CAS No.	7537-08-8
Molecular Formula	C10H10FNO2
Molecular Weight	195.19 g/mol
Synonyms	(2-Fluoro-3,4-dimethoxyphenyl)acetonitrile; 3,4-Dimethoxy-2-fluorobenzyl cyanide; 2-Fluoro-3,4-dimethoxybenzyl cyanide; 2-Fluoro-3,4-dimethoxybenzenecetonitrile; 7537-08-8; α-Cyano-2-fluoro-3,4-dimethoxytoluene; 2-Fluoro-3,4-dimethoxy-α-tolunitrile
EINECS	Contact for details

Quality Control

Our 2-Fluoro-3,4-Dimethoxyphenylacetonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in cGMP and ISO-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.