Description

Cortisone Succinate Sodium Salt is a water-soluble ester derivative of the glucocorticoid cortisone, designed for enhanced bioavailability and formulation flexibility. This compound is critical for creating stable, injectable pharmaceutical preparations where rapid systemic delivery is required. It is primarily utilized by pharmaceutical manufacturers and research institutions in the development and production of anti-inflammatory and immunosuppressive therapies.

Application

• Pharmaceutical Intermediates: A key starting material or intermediate in the synthesis of advanced corticosteroid APIs and finished dosage forms.
• Injectable Formulations: Used in the preparation of sterile injectable solutions and suspensions for hospital and clinical use.
• Anti-inflammatory Research: Serves as a standard or active agent in preclinical and clinical research studies targeting inflammatory pathways.
• Reference Standard: Employed as a high-purity analytical reference standard in quality control laboratories for HPLC, LC-MS, or pharmacopeial testing.
• Biochemical Studies: Utilized in cell culture and molecular biology research to study glucocorticoid receptor activity and gene expression.

Basic Information

Product Name	Cortisone Succinate Sodium Salt
CAS No.	7415-42-1
Molecular Formula	C25H31NaO8
Molecular Weight	482.50 g/mol
Synonyms	Cortisone 21-Hemisuccinate Sodium Salt; 17α,21-Dihydroxypregn-4-ene-3,11,20-trione 21-Hemisuccinate Sodium Salt; Sodium Cortisone Succinate; Cortisone Sodium Succinate; Cortisone 21-Succinate Sodium Salt; NSC 9704; Cortisone Hemisuccinate Sodium Salt
EINECS	Contact for details

Quality Control

Our Cortisone Succinate Sodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) detailing specifications such as assay, related substances, and residual solvents are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a dry environment and opened under low-humidity conditions when possible.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 3.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.