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D-Ribofuranoside, Methyl 2-Deoxy-2-Fluoro- CAS NO 7226-37-1


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CAS No.:7226-37-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

D-Ribofuranoside, Methyl 2-Deoxy-2-Fluoro- is a specialized fluorinated nucleoside derivative, a key synthetic intermediate in medicinal chemistry. This compound is valued for its role in the development of antiviral and anticancer therapeutics, particularly as a precursor for modified nucleoside analogs. It is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical synthesis units focused on nucleoside-based drug discovery.

Application

  • Pharmaceutical Intermediate: A critical building block for the synthesis of antiviral and anticancer nucleoside analogs.
  • Biochemical Research: Used in studies investigating enzyme mechanisms, particularly glycosyltransferases and nucleoside-processing enzymes.
  • Probe Development: Serves as a precursor for 18F-labeled PET (Positron Emission Tomography) imaging agents for diagnostic applications.
  • Antiviral Drug Synthesis: Key intermediate in the production chain for fluorinated nucleoside drugs targeting viral polymerases.
  • Glycobiology Studies: Employed in the synthesis of fluorinated sugar analogs to study carbohydrate-protein interactions.
  • Process Chemistry: Used in scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).

Basic Information

Product Name D-Ribofuranoside, Methyl 2-Deoxy-2-Fluoro-
CAS No. 7226-37-1
Molecular Formula C6H11FO5
Molecular Weight 182.15 g/mol
Synonyms Methyl 2-Deoxy-2-fluoro-D-ribofuranoside; 2-Deoxy-2-fluoro-D-ribofuranose methyl glycoside; 2-Fluoro-2-deoxy-D-ribofuranose methyl glycoside; Methyl 2-fluoro-2-deoxy-D-ribofuranoside; 1-O-Methyl-2-deoxy-2-fluoro-D-ribofuranose; 2-Fluoro-2-deoxymethyl riboside; 2'-Deoxy-2'-fluoromethyl riboside
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Quality Control

Our D-Ribofuranoside, Methyl 2-Deoxy-2-Fluoro- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation by atmospheric moisture.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to reference spectrum
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%
Specific Rotation Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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