Description

Chromomycin A3 is a potent aureolic acid group antibiotic isolated from *Streptomyces griseus*. This compound is highly valued for its specific binding to GC-rich regions of DNA, making it a critical tool in molecular biology and cytogenetics research. It is primarily utilized by research institutions, pharmaceutical R&D departments, and diagnostic laboratories for applications such as chromosome banding and the study of nucleic acid interactions.

Application

• Chromosome Banding (G-Banding): A key fluorescent stain in cytogenetics for the identification of chromosomes and chromosomal abnormalities.
• Molecular Biology Research: Used as a specific probe to study DNA structure, protein-DNA interactions, and gene regulation mechanisms.
• Antibiotic Activity Studies: Serves as a reference standard in microbiological assays to investigate its mechanism of action against Gram-positive bacteria.
• Biochemical Reagent: Employed in vitro for staining and visualization of nucleic acids in gel electrophoresis and other analytical techniques.
• Pharmaceutical Research: Investigated for its potential antitumor properties and as a model compound for developing new chemotherapeutic agents.

Basic Information

Product Name	Chromomycin A3
CAS No.	7059-24-7
Molecular Formula	C57H82O26
Molecular Weight	1183.25 g/mol
Synonyms	Chromomycin A3; Toyomycin; NSC-58514; Aburamycin B; Chromomycin-A3; 7-O-Methyl-chromomycin A3; Aureolic acid antibiotic
EINECS	Contact for details

Quality Control

Our Chromomycin A3 is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange-yellow powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Biological Activity	Assayed

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.