Description

Dichlorisone is a synthetic corticosteroid compound, specifically a halogenated derivative of prednisolone, known for its potent anti-inflammatory and immunosuppressive properties. This compound is a critical active pharmaceutical ingredient (API) and a valuable intermediate for advanced pharmaceutical synthesis. It is primarily utilized in the research and development of topical and systemic corticosteroid medications. Industries requiring high-purity steroid intermediates for pharmaceutical manufacturing will find this product essential for ensuring consistent quality and efficacy in final drug formulations.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of more complex corticosteroid APIs for anti-inflammatory drugs.
• Research & Development: Used in preclinical and clinical research to study glucocorticoid receptor activity and develop new therapeutic agents.
• Topical Formulations: A potential active ingredient in the development of creams, ointments, and lotions for treating dermatological conditions like eczema and psoriasis.
• Veterinary Medicine: Employed in the formulation of anti-inflammatory treatments for animals.
• Reference Standard: Used as an analytical standard in quality control laboratories for HPLC or GC method development and validation.
• Biochemical Research: A tool compound for investigating cellular signaling pathways mediated by steroid hormones.

Basic Information

Product Name	Dichlorisone
CAS No.	7008-26-6
Molecular Formula	C21H26Cl2O5
Molecular Weight	429.34 g/mol
Synonyms	9α,11β-Dichloro-17α,21-dihydroxypregna-1,4-diene-3,20-dione; 9α,11β-Dichloroprednisolone; Dichlorisonum; NSC-47439; 1,4-Pregnadiene-9,11-dichloro-17,21-diol-3,20-dione; 9α,11β-Dichloro-17α,21-dihydroxy-1,4-pregnadiene-3,20-dione
EINECS	Contact for details

Quality Control

Our Dichlorisone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical research and development. We provide full traceability and detailed Certificates of Analysis (COA) upon request, which include data from tests such as HPLC for purity, identification by IR spectroscopy, and residual solvent analysis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.