Description

2-Chloro-5-Nitrobenzotrifluoride is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both a nitro group and a trifluoromethyl group ortho to a chlorine atom, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the agrochemical and pharmaceutical sectors for the development of novel active ingredients.

Application

• Agrochemical Intermediate: A key precursor in the synthesis of modern herbicides, fungicides, and insecticides, leveraging the bioactivity of the nitro and trifluoromethyl groups.
• Pharmaceutical Synthesis: Serves as a building block for creating pharmacologically active compounds, particularly in the development of molecules with improved metabolic stability and bioavailability.
• Dye and Pigment Manufacturing: Used in the production of specialized dyes and pigments where the introduction of chlorine and nitro groups alters color properties and fastness.
• Liquid Crystal and Electronic Materials: Acts as an intermediate in the synthesis of advanced materials for electronic applications, including liquid crystal displays (LCDs).
• Organic Synthesis Research: Employed in academic and industrial R&D for cross-coupling reactions, nucleophilic aromatic substitutions, and as a scaffold for chemical library development.

Basic Information

Product Name	2-Chloro-5-Nitrobenzotrifluoride
CAS No.	777-37-7
Molecular Formula	C7H3ClF3NO2
Molecular Weight	225.55 g/mol
Synonyms	1-Chloro-2-nitro-4-(trifluoromethyl)benzene; 2-Chloro-α,α,α-trifluoro-5-nitrobenzene; 2-Chloro-5-nitro-α,α,α-trifluorotoluene; 2-Chloro-α,α,α-trifluoro-5-nitrotoluene; 5-Nitro-2-chlorobenzotrifluoride; Benzene, 1-chloro-2-nitro-4-(trifluoromethyl)-; 2-Chloro-5-nitrobenzylidene trifluoride
EINECS	212-300-6

Quality Control

Our 2-Chloro-5-Nitrobenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and reducing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	44 - 48 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.