Description

Pentafluorobenzonitrile is a high-purity fluorinated aromatic building block essential for advanced chemical synthesis. Its unique structure, featuring a nitrile group on a perfluorinated benzene ring, makes it a critical intermediate for creating complex molecules with tailored properties. This compound is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries for developing active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorine-containing drug candidates.
• Agrochemical Synthesis: Used in the production of advanced herbicides, pesticides, and fungicides where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated liquid crystals and organic light-emitting diode (OLED) materials, improving electronic properties and device performance.
• Polymer & Resin Modification: Incorporated as a monomer or cross-linking agent to create specialty polymers with enhanced chemical resistance, thermal stability, and low surface energy.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic aromatic substitution to introduce the pentafluorophenyl moiety into complex molecular architectures.
• Analytical Chemistry & Labeling: Can be used as a derivatization agent in gas chromatography (GC) or mass spectrometry (MS) for the detection and analysis of specific compounds.

Basic Information

Item	Details
Product Name	Pentafluorobenzonitrile
CAS No.	773-82-0
Molecular Formula	C7F5N
Molecular Weight	193.07 g/mol
Synonyms	Pentafluorobenzene carbonitrile; Perfluorobenzonitrile; 2,3,4,5,6-Pentafluorobenzonitrile; 2,3,4,5,6-Pentafluorobenzene carbonitrile; Pentafluorophenyl cyanide; Benzene carbonitrile, pentafluoro-; Pentafluorobenzonitrile (PFBN); Pentafluorobenzyl nitrile
EINECS	212-254-5

Quality Control

Our Pentafluorobenzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistent performance. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its nature as a strong acid/organic solvent and highly volatile compound, keep away from heat, sparks, and open flames. Ensure containers are kept tightly sealed when not in use to prevent evaporation and moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Purity (HPLC)	≥ 97.5%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.6 g/mL
Refractive Index (n20D)	~1.45

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.