Description

1,5-Difluoro-3-Iodo-2-Nitrobenzene is a high-purity halogenated nitrobenzene derivative, serving as a critical multi-functional building block in advanced organic synthesis. Its unique combination of fluorine, iodine, and nitro substituents on the aromatic ring makes it a versatile precursor for constructing complex molecular architectures. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated and iodinated active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting new therapeutic agents.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and pesticides, where the fluorine and iodine atoms can enhance biological activity and environmental stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for creating fluorinated aromatic cores in advanced electronic and optoelectronic materials.
• Cross-Coupling Reactions: The iodine atom is an excellent handle for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira), enabling rapid diversification of the benzene core.
• Nucleophilic Aromatic Substitution: The activated nitro and fluoro groups allow for selective substitution, facilitating step-wise functionalization.
• Chemical Biology Probes: Used in the design and synthesis of molecular probes and tags for imaging and diagnostic applications due to its halogen atoms.

Basic Information

Product Name	1,5-Difluoro-3-Iodo-2-Nitrobenzene
CAS No.	771-05-1
Molecular Formula	C6H2F2INO2
Molecular Weight	284.99 g/mol
Synonyms	3-Iodo-1,5-difluoro-2-nitrobenzene; 2-Nitro-1,5-difluoro-3-iodobenzene; 1,5-Difluoro-3-iodo-2-nitrobenzene; Benzene, 1,5-difluoro-3-iodo-2-nitro-; 771-05-1; 3-Iodo-2,6-difluoronitrobenzene
EINECS	Contact for details

Quality Control

Our 1,5-Difluoro-3-Iodo-2-Nitrobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the consistency and reliability required for critical research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This compound should be handled in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.