Description

4,4,4-Trifluoro-3-Hydroxy-3-(Trifluoromethyl)Butyrophenone, 97% Min. is a high-purity fluorinated organic building block characterized by its unique trifluoromethyl and hydroxyl functional groups. This compound is critical for introducing fluorine atoms into target molecules, a key strategy in modern pharmaceutical and agrochemical development to enhance metabolic stability, bioavailability, and lipophilicity. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for synthesizing novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides where the fluorine moiety improves environmental stability and efficacy.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, enhancing their dielectric and optical properties.
• Polymer Modification: Incorporated as a monomer or cross-linking agent to create specialty fluoropolymers with enhanced chemical and thermal resistance.
• Organic Synthesis Building Block: Utilized in academic and industrial research for constructing complex molecules via reactions involving its ketone and hydroxyl groups.
• Catalyst Ligand Precursor: Can be modified to create chiral ligands for asymmetric catalysis in fine chemical manufacturing.

Basic Information

Product Name	4,4,4-Trifluoro-3-Hydroxy-3-(Trifluoromethyl)Butyrophenone, 97% Min.
CAS No.	731-00-0
Molecular Formula	C11H8F6O2
Molecular Weight	286.17 g/mol
Synonyms	1,1,1,4,4,4-Hexafluoro-3-hydroxy-2-(trifluoromethyl)-4-phenylbutan-2-one; 3-Hydroxy-2-(trifluoromethyl)-1,1,1,4,4,4-hexafluoro-4-phenylbutan-2-one; 4,4,4-Trifluoro-3-hydroxy-3-(trifluoromethyl)butyrophenone; 1-Phenyl-1,1,4,4,4-hexafluoro-3-hydroxy-3-(trifluoromethyl)-2-butanone; Hexafluoro Derivative of Butyrophenone; F6-HBP; TFHTB
EINECS	Contact for details

Quality Control

Our 4,4,4-Trifluoro-3-Hydroxy-3-(Trifluoromethyl)Butyrophenone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure a minimum purity of 97% and compliance with stringent impurity profiles. Certificates of Analysis (COA) detailing identity, purity, and specific tests are provided with each shipment to guarantee traceability and meet the exacting standards of our global B2B clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is sensitive to strong alkalis and fluorides; keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	97.0% Min.
Water Content (KF)	0.5% Max.
Residue on Ignition	0.1% Max.
Heavy Metals (as Pb)	10 ppm Max.

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.