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3-Bromo-4-Fluoronitrobenzene CAS NO 701-45-1


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CAS No.:701-45-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-Bromo-4-Fluoronitrobenzene is a versatile halogenated nitrobenzene derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring bromine, fluorine, and nitro substituents, makes it an essential intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for developing active ingredients and functional materials.

Application

  • Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogenated aromatic cores.
  • Agrochemical Synthesis: Used in the development of herbicides, fungicides, and insecticides where the bromo-fluoro-nitro substitution pattern is beneficial.
  • Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and liquid crystals.
  • Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution reactions to introduce complex functionalities.
  • Dye and Pigment Intermediate: Used in the manufacture of specialized dyes and pigments where halogen atoms influence color and stability.

Basic Information

Product Name 3-Bromo-4-Fluoronitrobenzene
CAS No. 701-45-1
Molecular Formula C6H3BrFNO2
Molecular Weight 220.00 g/mol
Synonyms 1-Bromo-2-fluoro-5-nitrobenzene; 2-Fluoro-5-nitrobenzene bromide; 3-Bromo-4-fluoronitrobenzene; 4-Fluoro-3-bromonitrobenzene; Benzene, 1-bromo-2-fluoro-5-nitro-; 2-Fluoro-5-nitro-1-bromobenzene; 5-Nitro-2-fluorobromobenzene
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Quality Control

Our 3-Bromo-4-Fluoronitrobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly closed when not in use.

Specification

Item Specification
Appearance Light yellow to yellow crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Melting Point 48 - 52 °C
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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