Description

Dichlorisone Acetate is a synthetic corticosteroid derivative, recognized for its potent anti-inflammatory and immunosuppressive properties. This compound is a critical intermediate in the synthesis of advanced pharmaceutical actives, offering significant value in the development of targeted therapeutic agents. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of topical and systemic corticosteroid medications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potent corticosteroid drugs.
• Anti-inflammatory Agent Research: Used in preclinical and formulation research for developing new anti-inflammatory medications.
• Dermatological Preparations: Serves as an active ingredient or precursor in creams, ointments, and lotions for treating skin conditions like eczema and psoriasis.
• Veterinary Medicine: Employed in the formulation of anti-inflammatory treatments for animals.
• Biochemical Research: Used as a reference standard and tool in studying glucocorticoid receptor activity and metabolic pathways.
• Process Development: Utilized in optimizing and scaling up manufacturing processes for steroid-based pharmaceuticals.

Basic Information

Product Name	Dichlorisone Acetate
CAS No.	79-61-8
Molecular Formula	C24H30Cl2O6
Molecular Weight	485.40 g/mol
Synonyms	9α,11β-Dichloro-17α,21-dihydroxypregna-1,4-diene-3,20-dione 21-acetate; 9α,11β-Dichloroprednisolone 21-acetate; Dichlorisone 21-acetate; NSC-106965; 9α,11β-Dichloro-17α,21-dihydroxy-1,4-pregnadiene-3,20-dione 21-acetate; Prednisolone 9α,11β-dichloro-21-acetate
EINECS	Contact for details

Quality Control

Our Dichlorisone Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.