Description

Hydrocortamate is a synthetic corticosteroid ester, a derivative of hydrocortisone. This compound is valued for its anti-inflammatory and immunosuppressive properties, making it a key intermediate in the synthesis of specialized pharmaceutical formulations. It is primarily utilized by manufacturers in the pharmaceutical and life science research sectors for the development of topical and injectable corticosteroid products.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of potent corticosteroid APIs (Active Pharmaceutical Ingredients).
• Topical Corticosteroid Formulations: Used in the research and development of creams, ointments, and lotions for treating skin inflammation, eczema, and psoriasis.
• Injectable Steroid Preparations: Serves as a precursor for formulating long-acting injectable anti-inflammatory medications.
• Veterinary Medicine: Employed in the development of anti-inflammatory treatments for animals.
• Biochemical Research: Used as a reference standard and tool compound in studies of glucocorticoid receptor activity and steroid metabolism.
• Dermatological Product Development: Key ingredient in R&D for advanced dermatological treatments targeting specific inflammatory pathways.

Basic Information

Product Name	Hydrocortamate
CAS No.	76-47-1
Molecular Formula	C24H35NO6
Molecular Weight	433.54 g/mol
Synonyms	Hydrocortisone 21-Diethylaminoacetate; Hydrocortisone Diethylaminoacetate; 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione 21-(2-(diethylamino)acetate); NSC-527979; Hydrocortamate Hydrochloride (salt form); WIN-24540; Corticosteroid Ester 76-47-1
EINECS	200-964-7

Quality Control

Our Hydrocortamate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and specific tests for related substances and residual solvents. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications and results. Our quality standards are designed to meet the rigorous demands of pharmaceutical GMP applications and research-grade purity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Maximum Unknown Impurity	≤0.5%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.