Description

(1R)-1-(3-Fluorophenyl)Butylamine is a chiral amine building block of significant synthetic utility, characterized by its fluorinated aromatic ring and stereogenic center. This compound matters for its role as a key intermediate in the synthesis of advanced pharmaceutical agents and agrochemicals, where its specific stereochemistry and fluorine substitution are critical for biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and complex organic molecules.

Application

• As a chiral intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Building block for the development of agrochemicals, such as herbicides and fungicides, leveraging the fluorine atom for enhanced efficacy.
• Key starting material in asymmetric synthesis and medicinal chemistry research for structure-activity relationship (SAR) studies.
• Precursor for the preparation of chiral ligands and catalysts used in enantioselective transformations.
• Intermediate in the manufacture of specialty polymers and advanced materials with tailored properties.
• Used in the synthesis of diagnostic agents and biochemical tools for life science research.

Basic Information

Product Name	(1R)-1-(3-Fluorophenyl)Butylamine
CAS No.	698378-60-8
Molecular Formula	C10H14FN
Molecular Weight	167.22 g/mol
Synonyms	(R)-1-(3-Fluorophenyl)butan-1-amine; (1R)-1-(3-Fluorophenyl)-1-butanamine; (R)-α-Methyl-3-fluorobenzeneethanamine; (R)-3-Fluoro-α-ethylbenzylamine; (R)-1-(3-Fluorophenyl)butylamine; (R)-3'-Fluorobutropamine; (R)-Flephedrone intermediate; (1R)-1-(m-Fluorophenyl)butylamine
EINECS	Contact for details

Quality Control

Our (1R)-1-(3-Fluorophenyl)Butylamine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including chiral purity determination, to meet the stringent requirements of pharmaceutical development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.