Description

Benzonitrile, 4-Amino-3-Ethyl-2-(Trifluoromethyl)- (9Ci) is a specialized aromatic nitrile derivative featuring amino, ethyl, and trifluoromethyl substituents, making it a valuable fluorinated building block. This compound is critical for advanced organic synthesis, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought by research and development teams in the pharmaceutical, agrochemical, and advanced material sectors for creating complex molecules with enhanced properties.

Application

• Pharmaceutical Intermediate: A key fluorinated synthon in the synthesis of novel drug candidates, especially in kinase inhibitor and anti-cancer agent research.
• Agrochemical Synthesis: Used as a precursor in the development of advanced herbicides, fungicides, and pesticides with improved efficacy and environmental profiles.
• Liquid Crystal & OLED Material Research: Serves as a building block for fluorinated organic semiconductors and liquid crystal molecules due to its unique electronic properties.
• Dye & Pigment Intermediate: Employed in the synthesis of specialized, high-performance dyes and pigments where the trifluoromethyl group enhances lightfastness and chemical stability.
• Cross-Coupling Reactions: Utilized in palladium-catalyzed reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce complex aromatic systems into target molecules.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) exploring new synthetic methodologies and fluorine chemistry.

Basic Information

Product Name	Benzonitrile, 4-Amino-3-Ethyl-2-(Trifluoromethyl)- (9Ci)
CAS No.	697228-50-5
Molecular Formula	C10H9F3N2
Molecular Weight	214.19 g/mol
Synonyms	4-Amino-3-ethyl-2-(trifluoromethyl)benzonitrile; 2-(Trifluoromethyl)-4-amino-3-ethylbenzonitrile; 3-Ethyl-4-amino-2-trifluoromethylbenzonitrile; 4-Amino-3-ethyl-α,α,α-trifluoro-o-toluonitrile; 2-Cyano-6-ethyl-5-(trifluoromethyl)aniline; 5-Amino-4-ethyl-3-(trifluoromethyl)benzonitrile; Benzonitrile, 4-amino-3-ethyl-2-(trifluoromethyl)-; 697228-50-5
EINECS	Contact for details

Quality Control

Our Benzonitrile, 4-Amino-3-Ethyl-2-(Trifluoromethyl)- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Production adheres to cGMP (current Good Manufacturing Practice) guidelines where applicable. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support REACH compliance and can provide documentation for regulatory submissions upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 0.5%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.