Description

Oxiranecarboxylic Acid, 2-(Trifluoromethyl)-, (2R)- (9Ci) is a high-value, optically active chiral building block characterized by its epoxide and carboxylic acid functionalities. This compound matters for its role as a key synthetic intermediate in the production of complex molecules, where its stereochemistry and trifluoromethyl group impart unique physicochemical and biological properties. It is primarily needed by pharmaceutical, agrochemical, and advanced material research sectors for the development of novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Liquid Crystal & Polymer Chemistry: Serves as a monomer or precursor for fluorinated polymers and advanced materials with specific optical or surface properties.
• Asymmetric Catalysis & Ligand Design: Employed in the development of new chiral catalysts and ligands for enantioselective synthesis.
• Protease Inhibitor Research: The epoxide moiety makes it a potential candidate for the development of covalent protease inhibitors in medicinal chemistry.
• Fluorine Chemistry Research: A valuable substrate for studying the introduction and reactivity of fluorinated groups in complex molecular architectures.

Basic Information

Product Name	Oxiranecarboxylic Acid, 2-(Trifluoromethyl)-, (2R)- (9Ci)
CAS No.	693287-31-9
Molecular Formula	C4H3F3O3
Molecular Weight	156.06 g/mol
Synonyms	(2R)-2-(Trifluoromethyl)oxirane-2-carboxylic acid; (R)-2-(Trifluoromethyl)glycidic acid; (R)-3,3,3-Trifluoro-2-hydroxy-2-methylpropanoic acid, oxirane derivative; (R)-TFMGA; (R)-Trifluoromethyl glycidic acid; 2-Oxiranecarboxylic acid, 2-(trifluoromethyl)-, (2R)-; (R)-α-(Trifluoromethyl)glycidic acid
EINECS	Contact for details

Quality Control

Our Oxiranecarboxylic Acid, 2-(Trifluoromethyl)-, (2R)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting customer specifications and industry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.