Description

Benzonitrile, 3-(Aminomethyl)-5-(Trifluoromethyl)- (9Ci) is a high-value, multifunctional aromatic nitrile building block distinguished by its trifluoromethyl and aminomethyl substituents. This compound matters for its role in facilitating the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research where the introduction of fluorine atoms is critical for modulating bioactivity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functional polymers, liquid crystals, and organic electronic materials due to its aromatic core and polar functional groups.
• Fluorine Chemistry Building Block: Essential for introducing the trifluoromethyl moiety into complex molecular architectures in medicinal and synthetic chemistry programs.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	Benzonitrile, 3-(Aminomethyl)-5-(Trifluoromethyl)- (9Ci)
CAS No.	693250-09-8
Molecular Formula	C9H7F3N2
Molecular Weight	200.16 g/mol
Synonyms	3-(Aminomethyl)-5-(trifluoromethyl)benzonitrile; 5-(Trifluoromethyl)-3-cyanobenzylamine; [3-(Aminomethyl)-5-(trifluoromethyl)phenyl]methanamine; 3-Cyano-5-(trifluoromethyl)benzylamine; α-Amino-m-(trifluoromethyl)benzonitrile; 3-(Trifluoromethyl)-5-cyanobenzylamine; (3-Cyano-5-(trifluoromethyl)phenyl)methanamine
EINECS	Contact for details

Quality Control

Every batch of Benzonitrile, 3-(Aminomethyl)-5-(Trifluoromethyl)- (9Ci) is produced under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistency suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Keep away from strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.