Description

(E)-1-(1-Azepanyl)-4,4,5,5,5-Pentafluoro-1-Penten-3-One is a high-value, fluorinated organic building block featuring a unique seven-membered azepane ring. This compound matters for its role as a sophisticated intermediate in the synthesis of complex molecules, where its pentafluorinated moiety and ketone functionality enable precise structural modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Agrochemical Research: Used in the synthesis of novel herbicides and pesticides, where the fluorine atoms can enhance biological activity and environmental stability.
• Advanced Material Synthesis: Serves as a precursor for fluorinated polymers and specialty chemicals with unique surface properties and resistance.
• Ligand and Catalyst Development: The azepanyl group can be utilized to construct complex ligands for catalysis and molecular recognition applications.
• Chemical Biology Probes: Employed in the design of fluorinated probes and tags for studying biological mechanisms and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses serving the global fine chemical market.

Basic Information

Item	Details
Product Name	(E)-1-(1-Azepanyl)-4,4,5,5,5-Pentafluoro-1-Penten-3-One
CAS No.	692738-22-0
Molecular Formula	C11H14F5NO
Molecular Weight	271.23 g/mol
Synonyms	1-(1-Azepanyl)-4,4,5,5,5-pentafluoro-1-penten-3-one; (E)-1-(Azepan-1-yl)-4,4,5,5,5-pentafluoropent-1-en-3-one; 4,4,5,5,5-Pentafluoro-1-(hexahydro-1H-azepin-1-yl)-1-penten-3-one; 692738-22-0; Pentafluoro derivative of 1-(1-azepanyl)-1-penten-3-one
EINECS	Contact for details

Quality Control

Our (E)-1-(1-Azepanyl)-4,4,5,5,5-Pentafluoro-1-Penten-3-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.