Description

3-Iodo-5-(Trifluoromethyl)Benzonitrile is a high-value, multi-functional aromatic building block characterized by its unique combination of an iodine substituent and a trifluoromethyl group on a benzonitrile core. This compound is critical for introducing steric bulk and modulating electronic properties in advanced molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in cross-coupling reactions, medicinal chemistry, and the synthesis of liquid crystal materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions for constructing complex drug candidates and bioactive molecules.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the stability and lipophilicity imparted by the trifluoromethyl group.
• Material Science: Employed in the synthesis of specialized polymers, ligands for catalysis, and organic electronic materials due to its distinct electronic properties.
• Chemical Research: Acts as a versatile scaffold in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	3-Iodo-5-(Trifluoromethyl)Benzonitrile
CAS No.	691877-05-1
Molecular Formula	C8H3F3IN
Molecular Weight	312.97 g/mol
Synonyms	5-(Trifluoromethyl)-3-iodobenzonitrile; 3-Iodo-5-(trifluoromethyl)benzonitrile; 3-Cyano-5-iodobenzotrifluoride; 3-Iodo-alpha,alpha,α-trifluoro-m-toluonitrile; m-(Trifluoromethyl)-5-iodobenzonitrile; 691877-05-1; 5-Iodo-3-(trifluoromethyl)benzonitrile
EINECS	Contact for details

Quality Control

Our 3-Iodo-5-(Trifluoromethyl)Benzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.