Description

Benzeneacetonitrile, 2-Fluoro-3-Methoxy- (9Ci) is a specialized fluorinated aromatic nitrile building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both electron-withdrawing (nitrile, fluorine) and electron-donating (methoxy) substituents, makes it a versatile precursor for constructing complex heterocycles and active pharmaceutical ingredients (APIs). This high-purity intermediate is primarily targeted at research institutions and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-quality building blocks for their development pipelines.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for central nervous system (CNS) agents and kinase inhibitors.
• Agrochemical Synthesis: Used in the preparation of advanced herbicides and pesticides, where the fluorine atom can enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and liquid crystals with specific electronic or optical properties.
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research exploring the effects of fluorine substitution on reactivity and molecular properties.

Basic Information

Item	Detail
Product Name	Benzeneacetonitrile, 2-Fluoro-3-Methoxy- (9Ci)
CAS No.	672931-80-5
Molecular Formula	C9H8FNO
Molecular Weight	165.16 g/mol
Synonyms	2-Fluoro-3-methoxybenzyl cyanide; (2-Fluoro-3-methoxyphenyl)acetonitrile; 2-Fluoro-3-methoxybenzeneacetonitrile; 2-Fluoro-3-methoxybenzyl nitrile; α-Cyano-2-fluoro-3-methoxytoluene; 2-Fluoro-3-methoxy-α-tolunitrile; 2-Fluoro-3-methoxybenzenecarbonitrile (ambiguous, but sometimes used); 672931-80-5
EINECS	Contact for details

Quality Control

Every batch of Benzeneacetonitrile, 2-Fluoro-3-Methoxy- (9Ci) is produced and tested under a strict quality management system. We ensure compliance with high-purity standards suitable for research and commercial synthesis. Comprehensive analytical testing, including HPLC, GC, NMR, and MS, is performed to verify identity, purity, and impurity profiles. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.