Description

1-Fluoro-4-(4-Nitrophenyl)-2-(Trifluoromethyl)Benzene is a high-value, multi-functional fluorinated aromatic building block. This compound is engineered to provide a versatile scaffold for advanced synthesis, offering unique reactivity due to its combination of electron-withdrawing nitro and trifluoromethyl groups with a halogen handle. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for constructing complex molecules, including active pharmaceutical ingredients (APIs) and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the fluorine and trifluoromethyl groups enhance biological activity and environmental stability.
• Material Science Research: Serves as a monomer or precursor for developing specialty polymers and liquid crystals with tailored electronic and optical properties.
• Organic Electronics: Employed in the synthesis of charge-transport materials and emitters for organic light-emitting diodes (OLEDs) due to its electron-deficient aromatic core.
• Chemical Research & Development: A versatile building block for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution in academic and industrial R&D settings.

Basic Information

Product Name	1-Fluoro-4-(4-Nitrophenyl)-2-(Trifluoromethyl)Benzene
CAS No.	646054-51-5
Molecular Formula	C13H7F4NO2
Molecular Weight	285.20 g/mol
Synonyms	4'-Fluoro-4-nitro-2'-(trifluoromethyl)-1,1'-biphenyl; 2-(Trifluoromethyl)-4'-fluoro-4-nitro-1,1'-biphenyl; 1-Fluoro-4-(4-nitrophenyl)-2-(trifluoromethyl)benzene; 4-Fluoro-4'-nitro-2-trifluoromethylbiphenyl; [1,1'-Biphenyl]-4-carbonitrile, 4'-fluoro-2'-(trifluoromethyl)-; (4-Fluoro-2-(trifluoromethyl)phenyl)(4-nitrophenyl)
EINECS	Contact for details

Quality Control

Our production of 1-Fluoro-4-(4-Nitrophenyl)-2-(Trifluoromethyl)Benzene adheres to stringent quality management protocols. Every batch is analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality system is designed to support cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.