Description

3-Fluoro-2-(Bromomethyl)Benzonitrile is a versatile and high-value fluorinated aromatic building block. This compound is critical for introducing both fluorine and bromomethyl functional groups into complex molecular architectures, enabling precise structural modifications. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in kinase inhibitor and CNS-active molecule research.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Useful for constructing molecular probes and tags due to its reactive bromomethyl handle for bioconjugation.
• Custom Synthesis and Scale-up: Supplied for contract research organizations (CROs) and CDMOs engaged in custom synthesis projects from milligram to kilogram scale.

Basic Information

Item	Details
Product Name	3-Fluoro-2-(Bromomethyl)Benzonitrile
CAS No.	635723-84-1
Molecular Formula	C8H5BrFN
Molecular Weight	214.04 g/mol
Synonyms	2-(Bromomethyl)-3-fluorobenzonitrile; 3-Fluoro-2-(bromomethyl)benzonitrile; 2-Bromomethyl-3-fluorobenzonitrile; Benzonitrile, 3-fluoro-2-(bromomethyl)-; (3-Fluoro-2-cyanophenyl)methyl bromide
EINECS	Contact for details

Quality Control

Our 3-Fluoro-2-(Bromomethyl)Benzonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.