Description

Benzonitrile, 3-Fluoro-4-[(Methylamino)Methyl]- (9Ci) is a specialized fluorinated benzonitrile derivative with a methylamino-methyl side chain, serving as a valuable pharmaceutical intermediate and organic synthesis building block. Its unique molecular structure, combining a nitrile group with fluorine and a basic amine, makes it a versatile precursor for constructing complex molecules in medicinal chemistry. This compound is primarily utilized by research institutions and chemical manufacturers engaged in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, leveraging the fluorine atom for enhanced biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and liquid crystals due to its polar nitrile group and aromatic core.
• Chemical Biology Probes: Utilized to create fluorescent tags or molecular probes for studying biological processes.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring fluorinated aromatic compounds with amine functionality.

Basic Information

Product Name	Benzonitrile, 3-Fluoro-4-[(Methylamino)Methyl]- (9Ci)
CAS No.	633698-43-8
Molecular Formula	C9H9FN2
Molecular Weight	164.18 g/mol
Synonyms	3-Fluoro-4-[(methylamino)methyl]benzonitrile; 4-(Aminomethyl)-3-fluorobenzonitrile, N-Methyl-; 3-Fluoro-4-(N-methylaminomethyl)benzonitrile; 4-[(Methylamino)methyl]-3-fluorobenzonitrile; 3-Fluoro-4-(methylaminomethyl)benzonitrile; (3-Fluoro-4-cyanophenyl)-N-methylmethanamine
EINECS	Contact for details

Quality Control

Our production of Benzonitrile, 3-Fluoro-4-[(Methylamino)Methyl]- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials are subjected to comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to verify identity, potency, and impurity profiles. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all critical quality attributes. Our facilities operate under cGMP principles where applicable, supporting development from research to commercial scale.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to the presence of amine and nitrile functional groups, it should be stored separately from strong oxidizing agents and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.