Description

7-Fluoro-4-Methoxyisoquinolin-1(2H)-One is a high-purity, fluorinated isoquinolinone derivative serving as a critical advanced intermediate in modern organic synthesis. Its value lies in its unique molecular scaffold, which is essential for constructing complex pharmacophores and functional materials. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, oncology, and anti-infective agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging the biological activity of the fluorinated isoquinolinone core.
• Material Science Precursor: Serves as a monomer or functional unit in the synthesis of advanced organic materials, such as organic semiconductors or liquid crystals.
• Chemical Biology Probe: Employed in academic and industrial research to study enzyme mechanisms or as a fluorescent tag precursor due to its heterocyclic structure.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects requiring high-purity fluorinated heterocycles.

Basic Information

Product Name	7-Fluoro-4-Methoxyisoquinolin-1(2H)-One
CAS No.	630423-45-9
Molecular Formula	C₁₀H₈FNO₂
Molecular Weight	193.17 g/mol
Synonyms	7-Fluoro-4-methoxy-1,2-dihydroisoquinolin-1-one; 7-Fluoro-4-methoxy-2H-isoquinolin-1-one; 1(2H)-Isoquinolinone, 7-fluoro-4-methoxy-; 4-Methoxy-7-fluoro-1(2H)-isoquinolinone; 7-Fluoro-4-methoxyisoquinolin-1-ol (tautomer); 7-Fluoro-4-methoxy-1-isoquinolinol; 7-Fluoro-4-methoxy-1,2-dihydroisoquinoline-1-one
EINECS	Contact for details

Quality Control

Our 7-Fluoro-4-Methoxyisoquinolin-1(2H)-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.