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6,8-Difluoro-1,2,3,4-Tetrahydronaphthalen-2-Ol CAS NO 606492-31-3


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CAS No.:606492-31-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

6,8-Difluoro-1,2,3,4-Tetrahydronaphthalen-2-Ol is a fluorinated tetralin derivative, a versatile and valuable synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both fluorine substituents and a hydroxyl group on a partially saturated naphthalene core, makes it a critical building block for the development of complex molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets, leveraging the bioisosteric properties of fluorine.
  • Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and pesticides, where the fluorinated tetralin structure can enhance biological activity and environmental stability.
  • Material Science & Liquid Crystal Synthesis: Serves as a sophisticated monomer or intermediate for creating advanced organic materials, including liquid crystals for display technologies.
  • Organic Synthesis & Chemical Research: A valuable scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and the exploration of new chemical spaces in academic and industrial R&D labs.
  • Fluorine Chemistry Building Block: Utilized in the preparation of more complex fluorinated compounds, capitalizing on the reactivity of the hydroxyl group and the electronic influence of the fluorine atoms.

Basic Information

Product Name 6,8-Difluoro-1,2,3,4-Tetrahydronaphthalen-2-Ol
CAS No. 606492-31-3
Molecular Formula C₁₀H₁₀F₂O
Molecular Weight 184.18 g/mol
Synonyms 6,8-Difluoro-2-hydroxy-1,2,3,4-tetrahydronaphthalene; 6,8-Difluoro-2-tetralol; 2,3-Dihydro-6,8-difluoronaphthalen-1(4H)-one (tautomer); 6,8-Difluoro-1,2,3,4-tetrahydro-2-naphthol; 2-Hydroxy-6,8-difluoro-1,2,3,4-tetrahydronaphthalene; 6,8-Difluoro-2-naphthol, tetrahydro-; 6,8-Difluoro-α-tetralol
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Quality Control

Our 6,8-Difluoro-1,2,3,4-Tetrahydronaphthalen-2-Ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process development. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided to guarantee traceability and batch-to-batch reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.1%
Single Unknown Impurity (HPLC) ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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