Description

Benzonitrile, 5-Fluoro-2,3-Dihydroxy- (9Ci) is a high-purity, multi-functional aromatic nitrile derivative, distinguished by its fluorinated and dihydroxy substitution pattern. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block for synthesizing complex organic molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functional polymers, liquid crystals, and organic electronic materials due to its conjugated nitrile group and polar hydroxyl functionalities.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development, quality control, and regulatory submissions in GMP environments.

Basic Information

Product Name	Benzonitrile, 5-Fluoro-2,3-Dihydroxy- (9Ci)
CAS No.	606489-70-7
Molecular Formula	C7H4FNO2
Molecular Weight	153.11 g/mol
Synonyms	5-Fluoro-2,3-dihydroxybenzonitrile; 2,3-Dihydroxy-5-fluorobenzonitrile; 5-Fluoro-2,3-dihydroxybenzenecarbonitrile; 3-Cyano-4-fluoro-1,2-benzenediol; 606489-70-7 (CAS); 5-Fluoro-2,3-dihydroxybenzonitrile (9CI)
EINECS	Contact for details

Quality Control

Every batch of Benzonitrile, 5-Fluoro-2,3-Dihydroxy- (9Ci) is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and batch-to-batch consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. Our quality protocols are designed to meet the stringent requirements of GMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.