Description

2-Amino-6-Fluoro-4-Methoxy-Benzonitrile is a high-purity, multi-functional aromatic nitrile building block of significant interest in advanced organic synthesis. Its molecular structure, featuring strategically placed amino, fluoro, and methoxy substituents, makes it a versatile precursor for constructing complex heterocyclic systems and functional materials. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in the synthesis of fused heterocycles and targeted small molecules.
• Agrochemical Research: Used as a building block in the design and synthesis of new herbicides, fungicides, and insecticides with optimized properties.
• Material Science: Serves as a precursor for the synthesis of advanced organic materials, including liquid crystals, dyes, and functional polymers.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination) and nucleophilic aromatic substitution due to its reactive halogen and amino groups.
• Academic & Contract Research: A valuable reagent for methodological studies and the construction of complex molecular libraries in academic and CRO (Contract Research Organization) settings.

Basic Information

Product Name	2-Amino-6-Fluoro-4-Methoxy-Benzonitrile
CAS No.	601517-02-6
Molecular Formula	C8H7FN2O
Molecular Weight	166.15 g/mol
Synonyms	6-Fluoro-2-amino-4-methoxybenzonitrile; 4-Methoxy-2-amino-6-fluorobenzonitrile; 2-Amino-4-methoxy-6-fluorobenzonitrile; 6-Fluoro-4-methoxy-2-aminobenzonitrile; Benzonitrile, 2-amino-6-fluoro-4-methoxy-; 2-Amino-6-fluoro-4-methoxybenzonitrile; 601517-02-6; 2-Amino-6-fluoro-4-methoxy-benzonitrile
EINECS	Contact for details

Quality Control

Our 2-Amino-6-Fluoro-4-Methoxy-Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and process development. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically >97% by HPLC), and impurity profiles is provided with every shipment to guarantee traceability and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat sources and incompatible materials. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.