Description

Hydroxybenzylpindolol CAS NO 69925-27-5 is a specialized chemical compound belonging to the class of β-adrenergic receptor ligands, characterized by its distinct hydroxybenzyl and pindolol moieties. This compound is of significant value in pharmaceutical research and development, particularly for its potential as a key intermediate or reference standard in the synthesis and study of cardiovascular and neurological agents. It is primarily sought by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in the creation of novel therapeutic molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the multi-step synthesis of advanced β-blocker drug candidates and related active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or ligand in receptor binding assays to study β-adrenergic receptor interactions, selectivity, and signaling pathways.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the efficacy and selectivity of new chemical entities targeting cardiovascular and central nervous system disorders.
• Analytical Standard: Utilized as a high-purity certified reference material (CRM) for method development, validation, and quality control in analytical laboratories.
• Preclinical Development: Acts as a tool compound in pharmacological and toxicological studies during the early stages of drug discovery.

Basic Information

Product Name	Hydroxybenzylpindolol
CAS No.	69925-27-5
Molecular Formula	C22H28N2O4
Molecular Weight	384.47 g/mol
Synonyms	4-[2-Hydroxy-3-[(1-methyl-2-indol-4-yl)oxy]propyl]phenol; 1-(4-Hydroxyphenyl)-2-[(1-methyl-1H-indol-4-yl)oxy]-3-(isopropylamino)propan-1-ol; Hydroxybenzyl Pindolol; HBP; Pindolol hydroxybenzyl derivative
EINECS	Contact for details

Quality Control

Our Hydroxybenzylpindolol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR), purity assessment by HPLC, and control of related substances. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for materials intended for pharmaceutical research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if specified. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.