Description

5,12-Naphthacenedione, 8-Acetyl-10-((3-Amino-2,3,6-Trideoxy-α-L-Ly Xo-Hexopyranosyl)Oxy)-7,8,9,10-Tetrahydro-8-Hydroxy-1,6,11-Trimethoxy- , (8S-Cis)- is a structurally complex anthracycline derivative, representing a high-value synthetic intermediate in advanced pharmaceutical research. This compound is critical for its role in the development and synthesis of novel therapeutic agents, particularly in oncology. It is primarily sought by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the production of specialized active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel anthracycline-based chemotherapeutic agents and antibiotics.
• Biochemical Research: Used as a reference standard and probe compound in studies investigating DNA intercalation mechanisms and topoisomerase II inhibition.
• Anticancer Drug Development: A critical precursor for the research and development of next-generation cancer therapeutics targeting specific cellular pathways.
• Academic Research: Employed in university and institutional labs for medicinal chemistry projects focused on modifying anthracycline scaffolds to improve efficacy and reduce side effects.
• Process Chemistry: Utilized in scale-up and optimization studies for the commercial production of complex pharmaceutical molecules.

Basic Information

Product Name	5,12-Naphthacenedione, 8-Acetyl-10-((3-Amino-2,3,6-Trideoxy-α-L-Ly Xo-Hexopyranosyl)Oxy)-7,8,9,10-Tetrahydro-8-Hydroxy-1,6,11-Trimethoxy- , (8S-Cis)-
CAS No.	69804-37-1
Molecular Formula	C30H35NO12
Molecular Weight	601.60 g/mol
Synonyms	8-Acetyl-10-((3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione; (8S-cis)-8-Acetyl-10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione; Aclacinomycin T; Aclarubicin T; Anthracycline derivative T; 69804-37-1
EINECS	Contact for details

Quality Control

Our production of this high-purity intermediate adheres to strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to meet client-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when opening to prevent degradation.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.