Description

(R)-8-(((3-Amino-2,3,6-Trideoxy-α-L-Lyxo-Hexopyranosyl)Oxy)Acetyl) -7,8,9,10-Tetrahydro-6,8,11-Trihydroxy-1-Methoxy-5,12-Naphthacenedione is a structurally complex anthracycline derivative, a class of compounds renowned for their potent biological activity. This high-purity chemical is critical for advanced pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents. It serves as a key intermediate for researchers and manufacturers in the oncology and antibiotic drug discovery sectors, where precise molecular structure and purity are paramount for efficacy and safety studies. CAS No. 69804-35-9.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel anthracycline-based chemotherapeutic agents and antibiotics.
• Oncology Research: Used in biochemical and pharmacological studies to investigate mechanisms of action against various cancer cell lines.
• Antibiotic Development: Serves as a precursor in the research and development of next-generation antibiotic compounds.
• Biochemical Tool Compound: Employed in academic and industrial laboratories to study DNA intercalation and topoisomerase inhibition.
• Process Chemistry: Utilized in scale-up and optimization studies for the commercial production of complex active pharmaceutical ingredients (APIs).
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	(R)-8-(((3-Amino-2,3,6-Trideoxy-α-L-Lyxo-Hexopyranosyl)Oxy)Acetyl) -7,8,9,10-Tetrahydro-6,8,11-Trihydroxy-1-Methoxy-5,12-Naphthacenedione
CAS No.	69804-35-9
Molecular Formula	C26H29NO11
Molecular Weight	531.51 g/mol
Synonyms	Daunorubicin aglycone derivative; 13-Dihydrodaunorubicinone glycoside; (8R,10S)-8-Glycoloyl-10-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione; 3'-Amino-3'-deoxy-α-L-daunosaminyl daunorubicinone; Aclacinomycin A aglycone precursor; Anthracycline intermediate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of our (R)-8-(((3-Amino-2,3,6-Trideoxy-α-L-Lyxo-Hexopyranosyl)Oxy)Acetyl) -7,8,9,10-Tetrahydro-6,8,11-Trihydroxy-1-Methoxy-5,12-Naphthacenedione is manufactured and analyzed under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, meeting the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) including HPLC purity, spectral identification (IR, NMR), and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) or as specified on the label or COA. This compound is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided to maintain stability and potency.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.