Description

Heptaethylene Glycol Di(p-Toluenesulfonate) is a high-purity, functionalized polyethylene glycol derivative, serving as a critical bifunctional linker and protecting group reagent in advanced organic synthesis. Its value lies in its ability to introduce hydrophilic spacers or act as a leaving group for the controlled formation of ethers and esters under mild conditions. This compound is essential for researchers and manufacturers in the pharmaceutical, bioconjugation, and specialty polymer industries who require precise molecular assembly and modification.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of prodrugs, antibody-drug conjugates (ADCs), and polyethylene glycol (PEG)-modified therapeutic agents.
• Bioconjugation Linker: Used to attach drugs, dyes, or other functional molecules to proteins, peptides, or nanoparticles, utilizing the tosylate groups as reactive sites.
• Polymer Chemistry: Acts as a chain extender or cross-linking agent in the production of specialized polyethers, hydrogels, and dendrimers.
• Material Science: Employed in surface modification and functionalization to alter the hydrophilicity and biocompatibility of materials.
• Chemical Research: A versatile reagent in organic synthesis for nucleophilic substitution reactions to install ethylene glycol chains.
• Diagnostic Reagents: Used in the development of diagnostic assays and imaging probes that require water-soluble spacers.

Basic Information

Product Name	Heptaethylene Glycol Di(p-Toluenesulfonate)
CAS No.	69502-27-8
Molecular Formula	C28H42O13S2
Molecular Weight	650.76 g/mol
Synonyms	Heptaethylene glycol ditosylate; PEG7 ditosylate; 3,6,9,12,15,18,21-Heptaoxatritriacontane-1,33-diyl bis(4-methylbenzenesulfonate); Diethylene glycol heptamethylene ether ditosylate; 1,11-Bis(tosyloxy)-3,6,9-trioxaundecane (incorrect but common misnomer); p-Toluenesulfonic acid heptaethylene glycol diester; HeptaEG-di-OTs; TsO-PEG7-OTs
EINECS	Contact for details

Quality Control

Our Heptaethylene Glycol Di(p-Toluenesulfonate) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and production. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid or viscous liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.