Description

(2R)-(-)-Glycidyl Tosylate CAS NO 113826-06-5 is a high-value chiral epoxide building block, essential for the stereoselective synthesis of complex organic molecules. Its primary importance lies in its role as a versatile electrophile for introducing the (R)-glycidyl moiety, a key structural element in many active pharmaceutical ingredients (APIs) and fine chemicals. This product is critically needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require enantiomerically pure intermediates.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of β-blockers, antiviral agents, and other enantiopure drugs.
• Agrochemical Synthesis: Used in the production of chiral herbicides, fungicides, and plant growth regulators.
• Liquid Crystal & Advanced Material Precursor: Serves as a building block for chiral dopants and polymers with specific optical properties.
• Asymmetric Catalysis Research: A standard reagent for developing and testing new asymmetric ring-opening reactions.
• Peptide & Protein Modification: Employed for the selective modification of amino acid side chains to introduce epoxy functionalities.
• Cross-linking Agent for Polymers: Used in the formulation of specialty epoxy resins and adhesives requiring specific stereochemistry.

Basic Information

Product Name	(2R)-(-)-Glycidyl Tosylate
CAS No.	113826-06-5
Molecular Formula	C10H12O4S
Molecular Weight	228.26 g/mol
Synonyms	(R)-(-)-Glycidyl 4-Methylbenzenesulfonate; (R)-Glycidyl Tosylate; (2R)-Oxiran-2-ylmethyl 4-methylbenzenesulfonate; (-)-(R)-Glycidyl Tosylate; (R)-Epoxypropyl Tosylate; (R)-Epichlorohydrin Tosylate Equivalent; (R)-GPTs; Tosyl Glycidyl Ether, (R)-
EINECS	Contact for details

Quality Control

Our (2R)-(-)-Glycidyl Tosylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for chiral synthesis. Certificates of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles are provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C (refrigerated) for long-term stability. This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.