Description

H-Gly-Obzl p-Tosylate is a protected amino acid derivative, specifically the p-toluenesulfonate salt of benzyloxycarbonyl-glycine. This compound is a crucial building block in peptide synthesis, offering enhanced stability and solubility for complex coupling reactions. It is primarily utilized by pharmaceutical R&D departments and fine chemical manufacturers for the production of therapeutic peptides and novel bioactive compounds.

Application

• Solid-Phase Peptide Synthesis (SPPS): Serves as a protected glycine precursor for the sequential assembly of peptide chains.
• Solution-Phase Peptide Synthesis: Used in classical coupling methodologies for producing custom peptides and peptide fragments.
• Pharmaceutical Intermediate: A key raw material in the synthesis of peptide-based active pharmaceutical ingredients (APIs).
• Bioconjugation: Facilitates the site-specific attachment of peptides to other molecules, such as proteins, polymers, or drug delivery systems.
• Research & Development: Employed in academic and industrial labs for exploring new peptide structures and their biological activities.
• Production of Peptide Mimetics: Acts as a starting material for creating modified peptides with enhanced stability or bioavailability.

Basic Information

Product Name	H-Gly-Obzl p-Tosylate
CAS No.	114342-15-3
Molecular Formula	C17H19NO6S
Molecular Weight	365.40 g/mol
Synonyms	N-Carbobenzyloxyglycine p-Toluenesulfonate Salt; Z-Gly-OH·TsOH; Cbz-Glycine p-Tosylate; Benzyloxycarbonylglycine Tosylate; Glycine, N-[(phenylmethoxy)carbonyl]-, compd. with 4-methylbenzenesulfonic acid (1:1); N-(Benzyloxycarbonyl)glycine p-Toluenesulfonate; Z-Glycine Tosic Acid Salt; H-Gly-OBzl.TsOH
EINECS	Contact for details

Quality Control

Our H-Gly-Obzl p-Tosylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.