Description

Methyl (R)-2-Tosyloxy Propionate is a high-purity chiral building block and key synthetic intermediate. This compound is valued for its role in the stereoselective synthesis of complex molecules, where its specific configuration is critical for achieving desired biological activity. It is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing active pharmaceutical ingredients (APIs) and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of active pharmaceutical ingredients (APIs), particularly for β-amino acids and related compounds.
• Asymmetric Synthesis: Used in stereocontrolled chemical reactions to introduce the (R)-configuration into target molecules.
• Peptidomimetics Research: Serves as a building block for the development of peptide analogs and enzyme inhibitors in medicinal chemistry.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, catalysts, and ligands requiring high enantiomeric purity.
• Academic & R&D Laboratories: Utilized in method development and exploratory synthesis for novel organic compounds.

Basic Information

Product Name	Methyl (R)-2-Tosyloxy Propionate
CAS No.	109579-04-6
Molecular Formula	C11H14O5S
Molecular Weight	258.29 g/mol
Synonyms	(R)-Methyl 2-((4-methylphenyl)sulfonyloxy)propanoate; Methyl (R)-2-[(Tosyl)oxy]propionate; (R)-Methyl 2-(p-Toluenesulfonyloxy)propanoate; (R)-Methyl 2-Tosyloxypropanoate; (R)-2-(p-Toluenesulfonyloxy)propionic Acid Methyl Ester; (R)-MTSO Propionate; (R)-Methyl O-tosyl-Lactate (common name); (R)-MTsOP
EINECS	Contact for details

Quality Control

Our Methyl (R)-2-Tosyloxy Propionate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) specifying identity, purity, and enantiomeric excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.