Description

(R)-2-Benzyloxy-1,3-Propanediol 1- (p-Toluenesulfonate) is a high-value chiral building block and synthetic intermediate, specifically the (R)-enantiomer of a protected diol tosylate. This compound is critical for the stereoselective synthesis of complex molecules, offering precise control over the three-dimensional architecture of target compounds. It is primarily needed by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing active pharmaceutical ingredients (APIs), chiral ligands, and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly for antiviral, cardiovascular, and central nervous system (CNS) drugs.
• Asymmetric Synthesis: Used in the preparation of chiral catalysts, ligands (e.g., for transition metal catalysis), and auxiliaries to induce stereoselectivity in chemical reactions.
• Nucleoside/Nucleotide Chemistry: Serves as a protected, functionalized precursor for the synthesis of modified nucleosides and nucleotides with potential therapeutic applications.
• Polymer Science: Acts as a monomer or chain extender for creating chiral or functionalized polymers with specific optical or material properties.
• Natural Product Synthesis: Employed in the total synthesis of complex natural products where the (R)-configured 1,3-diol moiety is a structural component.
• Chemical Biology & Proteomics: Useful for synthesizing molecular probes, linkers, or tags for studying biological processes and protein interactions.

Basic Information

Product Name	(R)-2-Benzyloxy-1,3-Propanediol 1- (p-Toluenesulfonate)
CAS No.	119870-20-1
Molecular Formula	C17H20O5S
Molecular Weight	336.40 g/mol
Synonyms	(R)-1-O-(p-Toluenesulfonyl)-2-O-benzylglycerol; (R)-2-Benzyloxy-3-hydroxypropyl 4-methylbenzenesulfonate; (R)-1-Tosyl-2-benzyloxy-1,3-propanediol; (R)-2-Benzyloxy-1,3-propanediol 1-tosylate; (R)-1,3-Propanediol, 2-(phenylmethoxy)-, 1-(4-methylbenzenesulfonate); (R)-Glycerol 1-tosylate 2-benzyl ether; (R)-1-O-Tosyl-2-O-benzyl-sn-glycerol; BG-Ts (R)
EINECS	Contact for details

Quality Control

Our (R)-2-Benzyloxy-1,3-Propanediol 1- (p-Toluenesulfonate) is manufactured under strict quality control protocols to ensure high chemical and enantiomeric purity suitable for advanced synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing key parameters such as assay, enantiomeric excess (ee), and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for reliable, scalable supply to the pharmaceutical industry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.